Research Outputs

Publications & Preprints

Research outputs from the Genolux science team.

Preprints & Manuscripts

Research Papers

Note: DOIs marked [synthetic] are not real publications. Manuscript details are illustrative only.

Preprint — bioRxiv (2025)
Computational Enumeration of Hot-Spot Pharmacophores Across Oncology PPI Complexes
Voss E, Hale M, Sundaram R
bioRxiv preprint, 2025. doi:10.1101/2025.04.17.XXXXXX [synthetic — not a real DOI]
Preprint — bioRxiv (2025)
Rosetta Interface Scoring Calibrated for PPI Disruptor Prediction: A Benchmarking Study
Sundaram R, Okonkwo N, Voss E
bioRxiv preprint, 2025. doi:10.1101/2025.08.09.XXXXXX [synthetic — not a real DOI]
Submitted — Journal of Chemical Information and Modeling (2025)
PPI-Biased Fragment Library Design: Shape and Electrostatic Criteria for Interface-Targeting Compounds
Hale M, Voss E
Submitted to J. Chem. Inf. Model., under review as of December 2025
Presentations

Conference Presentations

Poster — ACS National Meeting, Spring 2025
A Computational Pipeline for PPI Interface Hot-Spot Enumeration and Fragment Scoring in Oncology Targets
Sundaram R, Hale M. American Chemical Society National Meeting, San Diego, March 2025
Division of Medicinal Chemistry. Poster abstract MEDI-412 [synthetic]
Invited Talk — Keystone Symposia, 2025
Toward Systematic Virtual Screening of PPI Interfaces: Lessons From Oncology Target Classes
Voss E. Keystone Symposia: Targeting Undruggable Proteins, Santa Fe NM, October 2025
Invited speaker, afternoon session [synthetic presentation]

Preprint Access & Collaboration

For preprint access, collaboration enquiries, or to discuss our methodology in detail, contact the research team directly.

Contact Research Team